Chiung-Yu Huang.

We observed that serious malarial anemia was usually due to an abrupt reduction in the hemoglobin concentration, exceeding 3 g per deciliter often. Severe malarial anemia in children is commonly thought to develop as a persistent process, but the pattern we noticed indicated a considerable contribution of the acute infection to hemoglobin loss.39,40 Both of these distinct dynamics of hemoglobin reduce could represent different pathologic procedures.39 Our study provides direct evidence that severe malaria is unlikely to recur but that it commonly occurs after previous infections, including high-density infections.

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