The significance levels for these analyses were equal to approximately 0.0002, 0.0030, 0.0111, and 0.0461, respectively. At each analysis, a step-down tests procedure was used. We in comparison the AC-T group with each trastuzumab-containing program at a significance level equal to half alpha to take into account multiple tests. If both comparisons were significant, we compared the two trastuzumab regimens at a significance add up to alpha. The first interim analysis was completed following the observation of 322 disease-free survival events in September 2005. At that right time, the efficacy boundaries had been crossed and demonstrated a big change in disease-free survival events in favor of both AC-T plus trastuzumab and TCH, in comparison with AC-T, with no significant difference between AC-T plus trastuzumab and TCH.By comparison, only 12 % of patients dying at home were unable to discover any peace. Being at home during one’s final days might help a person consider solace in the life they lived, said Don Schumacher, cEO and president of the National Hospice and Palliative Treatment Organization, based in Alexandria, Va. The smells, the familiarity, the comfort, the love, the items they’ve helped to create, the backyard they’ve built – – all of this is around them, Schumacher said. It generates such a feeling of accomplishment and nurturing and caring. The study also discovered that relatives reported that people who died in the home experienced no more pain than those who died receiving hospital care. Many people with cancer justifiably fear pain, Gomes said.