Evaluation of additional covariates is referred to in the Supplementary Appendix, obtainable with the full text of this article at NEJM.org. Clinical End Points Ischemic vascular disease was defined as either ischemic cardiovascular disease or ischemic cerebrovascular disease. Information on diagnoses of ischemic heart disease and ischemic cerebrovascular disease was gathered and verified through an assessment of all medical center admissions and diagnoses entered in the Danish National Individual Registry, all causes of loss of life entered in the National Danish Factors behind Loss of life Registry, and medical records from hospitals and general practitioners. Details of these and various other end points are provided in the Supplementary Appendix.9 GRCh37.p5) .The researchers calculated that this mix of factors would cause green ocean turtles living in even more polluted waters to consume 14 times as very much arginine as turtles in less polluted seas. ‘The energy and arginine content of may therefore become a sort of one-two punch for advertising this disease,’ the researchers wrote. The considerable research provides implications for other forms of marine life affected by pollution, the scientists said. ‘It’s not just green turtles, but fish and coral reefs which have similar illnesses in these places,’ Van Houtan said.. Diana W. Bianchi, M.D., R. Lamar Parker, M.D., Jeffrey Wentworth, M.D., Rajeevi Madankumar, M.D., Craig Saffer, M.D., Anita F.