What’s this lesion? A 35-year-old man had an asymptomatic, 5 mm papule on his remaining shoulder which acquired persisted for six months. Close examination showed a sharply circumscribed, elevated red papule with a yellowish hue . No related lesions were found on general examination of his skin. Excision biopsy demonstrated an elevated epidermis under which there is a diffuse infiltrate of histiocytes . Most of the histiocytes were multinucleated and experienced a central wreath of nuclei with a foamy periphery . There is a background of lymphocytes, plasma and eosinophils cells between your histiocytes.. A red papule with a yellowish hue A 35-year-old guy presents with an asymptomatic yellowish-crimson papule on his shoulder.They were individuals from nine Puget Sound region primary-care treatment centers in western Washington state. The treatment centers were chosen for their socioeconomic and racial/ethnic diversity and were demographically like the area’s population. Initial enrollment of patients took place between 2000 and 2002, and the sufferers had been studied for five years. Patients diagnosed with dementia were excluded from the study already.