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Reclassification was more often right than incorrect with a measured GFR threshold of significantly less than 60 ml per minute per 1.73 m2 . For participants with a creatinine-based approximated GFR of 45 to 74 ml each and every minute per 1.73 m2, the combined equation improved classification , with correct reclassification of 28 of 166 individuals with a creatinine-based estimated GFR of 45 to 59 ml per minute per 1.73 m2 to 60 ml per minute per 1.73 m2 or higher. In this subgroup, outcomes were related when the cystatin C equation was utilized. Results were consistent across most of the subgroups defined by age, sex, diabetes position, body-mass index, and additional measured GFR thresholds .