23.2 percent with bevacizumab, P=0.1 percent without bevacizumab vs. 51.5 percent with bevacizumab, P=0.34). The effects of adding bevacizumab on the prices of pathological complete response in the 1166 eligible patients were very similar to those in the primary-analysis cohort .).1 percent vs. 23.5 percent, P=0.8 percent vs. 27.6 percent, P=0.10) or the docetaxel regimen . The P value for the test for homogeneity of the odds ratios relating to chemotherapy routine was 0.07. There was an increase in the rate of pathological complete response in the nodes and breast with bevacizumab therapy, however the difference in the overall cohort was not significant .As in smaller sized randomized trials involving surgeons who have been experienced in off-pump CABG, the rate of patency of left internal thoracic-artery grafts left anterior descending artery inside our trial was excellent . This finding was much like findings by Widimsky et al.,25 who reported an arterial-graft patency price of 91 percent for both methods, and Puskas et al.,26 who reported arterial-graft patency rates of 94.1 percent for off-pump CABG and 98.1 percent for on-pump CABG.