As the real number of instances of STEC-HUS has risen to unprecedented levels, PEI, leading physicians, and Alexion have agreed that execution of a scientific trial is the best environment to make sure that the investigational therapy is definitely provided to individuals in a controlled manner to support security and potential efficacy in this severe clinical setting. The study aims to include all sufferers who are receiving eculizumab in the current STEC-HUS outbreak. We have an unprecedented number of patients with STEC-HUS who are severely ill with a broad selection of clinical manifestations. As we continue to react quickly to this public health crisis, we believe that the simplest way to measure the protection and efficacy of eculizumab in treating STEC-HUS individuals is through a controlled research, stated Rolf Stahl, M.D., Chairman, Department of Nephrology, University Hospital Hamburg-Eppendorf UKE and lead investigator of the clinical trial.Berry, Ph.D., Constance T. Cirrincione, M.S., Maria Theodoulou, M.D., Ann M. Mauer, M.D., Alice B. Kornblith, Ph.D., Ann H. Partridge, M.D., M.P.H., Lynn G. Dressler, Ph.D., Harvey J. Cohen, M.D., Heather P. Becker, Patricia A. Kartcheske, B.S., Judith D. Wheeler, M.P.H., Edith A. Perez, M.D., Antonio C. Wolff, M.D., Julie R. Gralow, M.D., Harold J. Burstein, M.D., Ph.D., Ahmad A. Mahmood, M.D., Gustav Magrinat, M.D., Barbara A. Parker, M.D., Ronald D. Hart, M.D., Debjani Grenier, M.D., Larry Norton, M.D., Clifford A. Hudis, M.D., and Eric P. Winer, M.D. For the CALGB Investigators: Adjuvant Chemotherapy in Older Women with Early-Stage Breast Cancer Age is the major risk aspect for breast cancer.1 In the usa, the average age at the diagnosis of breast cancers is approximately 63 years, and most deaths from breast cancer occur in women 65 years of age or older.